Physicians and Scholars Cooperation Group

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The Chemical Agent Connection to ImmuneACCORD Technology

The connection between the inflammatory pathology of insults such as radiation, trauma and chemical agents and that associated with many diseases was a strong predictor for ImmuneACCORD technology. Multi-Threat Medical Countermeasures (MTMC) technology to interdict the common inflammatory pathology for multiple classes of chemical warfare agents was further proposed to improve public health (Cowan et al. 2004). The concept of such broad spectrum chemical countermeasures was later incorporated as a component of Homeland Security Presidential Directive/HSPD-18. Medical Countermeasures against Weapons of Mass Destruction. January 31, 2007.

"It is not presently feasible to develop and stockpile medical countermeasures against every possible threat." ...Creating defenses against a finite number of known or anticipated agents is a sound approach for mitigating the most catastrophic CBRN threats; however, we also must simultaneously employ a broad-spectrum "flexible" approach to address other current and future threats. ...Although significant technological, organizational, and procedural challenges will have to be overcome, such a balanced strategic approach would mitigate current and future CBRN threats and benefit public health."

Physicians and Scholars Cooperation Group

AT: University of Connecticut, Dept. Molecular & Cell Biology,
BSP 305 91 North Eagleville Road, Unit 3125,
Storrs, Connecticut 06269-3125 U.S.A.
TEL: (860) 816-6963; FAX: (860) 486-4331
Email: david.haines@uconn.edu

INFLAMMATORY DISEASE IN CHEMICAL VICTIMS
A MODEL FOR HEALTHCARE WORLDWIDE:

ImmuneACCORD Conflicts in the Middle East 1980-1991 exposed residents of 3 nations: Iran, Iraq and Kuwait, to a diverse spectrum of highly toxic materials, including chemical weapons, partly combusted raw petroleum and many other toxicants that can cause acute injury and/or chronic disease over many decades.

This horrific tragedy prompted at least some modest international cooperation that resulted in SPG member Dr. David Haines organizing PSCG. Washington Post, June 2006: Reaching Out to Iran. Research on Gas Victims May Offer a Bridge. By David Ignatius. » Washington Post: Reaching Out to Iran

PSCG developed a general approach to prevention of and therapy for inflammatory pathology and disease associated with chemical exposures. The PSCG mission and ImmuneACCORD™ model for healthcare delivery allowed Summative Synergy Product Groups (SPG) and PSCG efforts to dovetail towards helping chemical victims and achieving healthcare worldwide.

The PSCG Mission:

Define scope of problem.

Identify major trends in health status of chemical exposed and normal populations. Use this data to help predict public health burden and national healthcare priorities in Iraq, Iran and Kuwait.

Define health problems.

Perform immunological and molecular biological studies of disease.

Develop novel therapeutic strategies.

Treatments must be low-cost and non-toxic and can include public health, dietary phytonutrition and phytotherapy and other pharmaceutical elements.

Design healthcare delivery worldwide.

Healthcare delivery must target local medical problems and be sustainable within the resource and constraints of each nation.

"ImmuneACCORD technology may do for healthcare what the personal computer did for information technology, allowing individuals more control over and access to affordable healthcare..."

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"ImmuneACCORD^TM offers access to & more control over a better diet which maximizes phytonutrition & promotes good health. ImmuneACCORD phytonutrients may do for nutritional health what the personal computer did for information technology."

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Phytochemicals are plant-derived chemical compounds under scientific research for their potential health-promoting properties. "Phytonutrients" are plant-derived essential nutrients scientifically confirmed as important to human health. -- Wikipedia.org

Synergy (from the Greek syn-ergo meaning working together) is the term used to describe a situation where the final outcome of a system is greater than the sum of its parts. -- Wikipedia.org

Homeostasis (from Greek: "to stand" lit. "to stand equally"; coined by Walter Bradford Cannon) is the property of either an open system or a closed system, especially a living organism, that regulates its internal environment so as to maintain a stable, constant condition. Multiple dynamic equilibrium adjustment and regulation mechanisms make homeostasis possible. The concept came from that of milieu interieur that was created by Claude Bernard and published in 1865. -- Wikipedia.org

In biology, the term epigenetics refers to heritable changes in phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence (hence the name epi - "in addition to" - genetics). -- Wikipedia.org

Fat located in the peritoneal cavity (abdominal area) that surrounds the body's internal organs.

A biomarker is a substance used as an indicator of a biologic state. It is a characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. -- Wikipedia.org

Nutraceutical, a portmanteau of nutrition and pharmaceutical, refers to extracts of foods claimed to have a medicinal effect on human health. The nutraceutical is usually contained in a medicinal format such as a capsule, tablet or powder in a prescribed dose. -- Wikipedia.org

ImmuneACCORD technology is made possible by the ever-increasing scientific proof for a common role for abnormal inflammation in insult, injury and most disease, and scientific experimentation on the influence of dietary levels of plant phytonutrients on inflammatory pathways, the epigeneome and disease.

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